HPE Full Form
HPE Full Form-What Is HPE? A Doctor Explains The Meaning Behind This Medical Term : HPE is the failure of the prosencephalon, or forebrain, to develop normally. The forebrain is a region of the brain in the fetus that develops into parts of the adult brain, including the cerebral cortex.
HPE Full Form
FAQs About HPE:
"When we went and looked at it, it didn't look right," Thomas Brueckner, chair of the department of developmental biology at the Medical College of Wisconsin in Milwaukee, said in an interview with MNN. "It was fairly stunning that you would miss something like that." The researchers discovered the problem in 1994 during a study of 20 babies who were born with a forebrain abnormality. The baby had an extra part of the prosencephalon, or forebrain. In the first trimester, the areas in the brain that would develop into the cerebral cortex, the part of the brain that controls language, are poorly developed. These areas, the developing brain tissue, form out of the forebrain. "You don't want those cells to leave your body and be in a completely different part of the brain," says Brueckner.
HPE is characterized by symptoms that are delayed. Usually, signs of HPE appear when the baby is more than 12 weeks old. The signs may include: Anencephaly, a rare, undescended cranium, with anencephaly being the most common. Headaches Hearing loss Strokes or other brain-related injuries Nervous system problems Hepatitis Down syndrome Hemorrhaging Pulmonary issues Herpes Alzheimer’s Disease Diagnosis Tests that can be used to diagnose HPE are the following: Electroencephalogram (EEG) Circumstances Anencephaly: It is a condition that occurs during the second and third trimester of pregnancy. In this condition, the skull doesn’t fully form around the brain. In a medical setting, anencephaly occurs from the fluid not developing. This is typically found in utero.
There are several different causes of HPE, including the following: Hormonal imbalances Perinatal infection, such as rubella or cytomegalovirus Transfusion of maternal serum during early pregnancy, or certain drugs during pregnancy HEPES Information Perinatal infection is a major cause of HPE. During pregnancy, the immune system is suppressed in order to protect the developing fetus from infection, thus the baby has little to no antibodies to protect against infection. In cases of HPE, infection occurs during the first trimester and spreads to the brain. Prevention Of HPE The leading recommendation for prevention of HPE is vaccination against rubella (Rubeola), an infectious disease that can cause severe birth defects and cause death in certain cases.
HPE is diagnosed using an ultrasound scan. Diagnosis is based on the amount of fluid in the brain and its location. If the fluid is more in one region than the other, a diagnosis is likely. Some children with HPE have no apparent problems. Others may have learning disabilities and short-term memory loss.
Holoprosencephaly affects approximately 1 in every 20,000 babies born in the U.S., according to the Centers for Disease Control and Prevention (CDC). A parent's research into the disorder may yield unexpected suggestions for coping with their child's disability. Parents may learn to adapt their environment in order to help their child become more mobile or to use a wheelchair. For example, moving the furniture away from the walls may provide mobility to the child. Cognitive As an infant, many HPE patients appear normal. However, by the age of 2 months, the child begins to lose motor skills. The child will eventually have difficulty chewing and swallowing. A child with HPE can also experience trouble thinking and learning.